Distribution differences in prognostic copy number alteration profiles in IDH-wild-type glioblastoma cause survival discrepancies across cohorts

The diagnosis and prognostication of glioblastoma (GBM) remain to be solely dependent on histopathological findings and few molecular markers, despite the clinical heterogeneity in this entity. To address this issue, we investigated the prognostic impact of copy number alterations (CNAs) using two p...

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Pubblicato in:Acta Neuropathol Commun
Autori principali: Umehara, Toru, Arita, Hideyuki, Yoshioka, Ema, Shofuda, Tomoko, Kanematsu, Daisuke, Kinoshita, Manabu, Kodama, Yoshinori, Mano, Masayuki, Kagawa, Naoki, Fujimoto, Yasunori, Okita, Yoshiko, Nonaka, Masahiro, Nakajo, Kosuke, Uda, Takehiro, Tsuyuguchi, Naohiro, Fukai, Junya, Fujita, Koji, Sakamoto, Daisuke, Mori, Kanji, Kishima, Haruhiko, Kanemura, Yonehiro
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6580599/
https://ncbi.nlm.nih.gov/pubmed/31215469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-019-0749-8
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