4-Aryl Pyrrolidines as Novel Orally Efficacious Antimalarial Agents. Part 2: 2-Aryl-N-(4-arylpyrrolidin-3-yl)acetamides

[Image: see text] Malaria is caused by infection from the Plasmodium parasite and kills hundreds of thousands of people every year. Emergence of new drug resistant strains of Plasmodium demands identification of new drugs with novel chemotypes and mechanisms of action. As a follow up to our evaluati...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:ACS Med Chem Lett
Prif Awduron: Meyers, Marvin J., Liu, Jianguang, Liu, Zhijun, Ma, Hongwei, Dai, Linglin, Adah, Dickson, Zhao, Siting, Li, Xiaofen, Liu, Xiaorong, Lu, Yongzhi, Huang, Yanhui, Tu, Zhengchao, Chen, Xiaoping, Tortorella, Micky D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Chemical Society 2019
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6580545/
https://ncbi.nlm.nih.gov/pubmed/31223456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.9b00123
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