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Differential action of TGR5 agonists on GLP-2 secretion and promotion of intestinal adaptation in a piglet short bowel model

Enteroendocrine L cells and glucagon-like peptide 2 (GLP-2) secretion are activated in the intestinal adaptation process following bowel resection in patients with short bowel syndrome. We hypothesized that enteral activation of Takeda G protein-coupled receptor 5 (TGR5), expressed in enteroendocrin...

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Bibliografische gegevens
Gepubliceerd in:Am J Physiol Gastrointest Liver Physiol
Hoofdauteurs: Lin, Sen, Stoll, Barbara, Robinson, Jason, Pastor, Jose J., Marini, Juan C., Ipharraguerre, Ignacio R., Hartmann, Bolette, Holst, Jens J., Cruz, Stephanie, Lau, Patricio, Olutoye, Oluyinka, Fang, Zhengfeng, Burrin, Douglas G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Physiological Society 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6580240/
https://ncbi.nlm.nih.gov/pubmed/30920308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00360.2018
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