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Prematurity reduces citrulline-arginine-nitric oxide production and precedes the onset of necrotizing enterocolitis in piglets

Necrotizing enterocolitis (NEC) is associated with low plasma arginine and vascular dysfunction. It is not clear whether low intestinal citrulline production, the precursor for arginine synthesis, occurs before and thus predisposes to NEC or if it results from tissue damage. This study was designed...

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Detalhes bibliográficos
Publicado no:Am J Physiol Gastrointest Liver Physiol
Main Authors: Robinson, Jason L., Smith, Victoria A., Stoll, Barbara, Agarwal, Umang, Premkumar, Muralidhar H., Lau, Patricio, Cruz, Stephanie M., Manjarin, Rodrigo, Olutoye, Oluyinka, Burrin, Douglas G., Marini, Juan C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6415715/
https://ncbi.nlm.nih.gov/pubmed/30048597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00198.2018
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