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Prematurity reduces citrulline-arginine-nitric oxide production and precedes the onset of necrotizing enterocolitis in piglets

Necrotizing enterocolitis (NEC) is associated with low plasma arginine and vascular dysfunction. It is not clear whether low intestinal citrulline production, the precursor for arginine synthesis, occurs before and thus predisposes to NEC or if it results from tissue damage. This study was designed...

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Veröffentlicht in:Am J Physiol Gastrointest Liver Physiol
Hauptverfasser: Robinson, Jason L., Smith, Victoria A., Stoll, Barbara, Agarwal, Umang, Premkumar, Muralidhar H., Lau, Patricio, Cruz, Stephanie M., Manjarin, Rodrigo, Olutoye, Oluyinka, Burrin, Douglas G., Marini, Juan C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6415715/
https://ncbi.nlm.nih.gov/pubmed/30048597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00198.2018
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