Costunolide inhibits matrix metalloproteinases expression and osteoarthritis via the NF-κB and Wnt/β-catenin signaling pathways

Osteoarthritis (OA) is a chronic joint disease involving cartilage erosion and matrix degradation. Costunolide is a sesquiterpene lactone that has been demonstrated to exert anti-inflammatory activities in a wide variety of cells. The aim of the present study was to investigate the effect of costuno...

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Gepubliceerd in:Mol Med Rep
Hoofdauteurs: He, Yuzhe, Moqbel, Safwat Adel Abdo, Xu, Langhai, Ran, Jisheng, Ma, Chiyuan, Xu, Kai, Bao, Jiapeng, Jiang, Lifeng, Chen, Weiping, Xiong, Yan, Wu, Lidong
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: D.A. Spandidos 2019
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Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6580033/
https://ncbi.nlm.nih.gov/pubmed/31115524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2019.10239
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