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Crocin protects against dexamethasone-induced osteoblast apoptosis by inhibiting the ROS/Ca(2+)-mediated mitochondrial pathway

Osteoblast apoptosis has been identified as an important event in the development of glucocorticoid (GC)-induced osteoporosis and osteonecrosis of the femoral head. Crocin, a bioactive ingredient of saffron, has been demonstrated to induce antiapoptotic effects on numerous types of cell in vitro; ho...

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Bibliografiske detaljer
Udgivet i:Mol Med Rep
Main Authors: Nie, Zhigang, Deng, Shuang, Zhang, Lei, Chen, Sen, Lu, Qiang, Peng, Hao
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6580004/
https://ncbi.nlm.nih.gov/pubmed/31115574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2019.10267
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