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microRNA-126 Is a Tumor Suppressor of Granulosa Cell Tumor Mediated by Its Host Gene EGFL7

MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expression at a post-transcriptional level. We examined the role of miR-126 in granulosa cell tumor (GCT) of the ovaries. In tissues from malignant GCT patients miR-126 expression was repressed. We showed that miR-126 could inhibit proli...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Tu, Jiajie, Cheung, Hoi-Hung, Lu, Gang, Chan, Clement Leung-Kwok, Chen, Zijiang, Chan, Wai-Yee
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6579899/
https://ncbi.nlm.nih.gov/pubmed/31245291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.00486
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