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MicroRNA-10a promotes granulosa cells tumor development via PTEN-AKT/Wnt regulatory axis

We have previously reported that microRNA-10 family could disturb normal development of granulosa cells (GC) during follicle formation. In the current study, the effect of miR-10a on granulosa cell tumor (GCT), a subtype of ovarian cancer, was examined. Strong miR-10a signal was detected in tissues...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Tu, Jiajie, Cheung, Hoi-Hung, Lu, Gang, Chen, Zijiang, Chan, Wai-Yee
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6197200/
https://ncbi.nlm.nih.gov/pubmed/30348959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1117-5
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