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Morpholino-induced exon skipping stimulates cell-mediated and humoral responses to dystrophin in mdx mice
Exon skipping is a promising genetic therapeutic strategy for restoring dystrophin expression in the treatment of Duchenne muscular dystrophy (DMD). The potential for newly synthesized dystrophin to trigger an immune response in DMD patients, however, is not well established. We have evaluated the e...
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| Udgivet i: | J Pathol |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6579705/ https://ncbi.nlm.nih.gov/pubmed/30883742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.5263 |
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