Morpholino-induced exon skipping stimulates cell-mediated and humoral responses to dystrophin in mdx mice

Exon skipping is a promising genetic therapeutic strategy for restoring dystrophin expression in the treatment of Duchenne muscular dystrophy (DMD). The potential for newly synthesized dystrophin to trigger an immune response in DMD patients, however, is not well established. We have evaluated the e...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:J Pathol
Κύριοι συγγραφείς: Vila, Maria Candida, Novak, James S., Klimek, Margaret Benny, Li, Ning, Morales, Melissa, Fritz, Alexander G., Edwards, Katie, Boehler, Jessica F., Hogarth, Marshall W., Kinder, Travis B., Zhang, Aiping, Mazala, Davi, Fiorillo, Alyson A., Douglas, Bonnie, Chen, Yi-Wen, van den Anker, John, Lu, Qi Long, Hathout, Yetrib, Hoffman, Eric P., Partridge, Terence A., Nagaraju, Kanneboyina
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2019
Θέματα:
Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6579705/
https://ncbi.nlm.nih.gov/pubmed/30883742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.5263
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