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Distinct roles of myofibroblast-specific Smad2 and Smad3 signaling in repair and remodeling of the infarcted heart
TGF-βs regulate fibroblast responses, by activating Smad2 or Smad3 signaling, or via Smad independent pathways. We have previously demonstrated that myofibroblast-specific Smad3 is critically implicated in repair of the infarcted heart. However, the role of fibroblast Smad2 in myocardial infarction...
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| Publicado no: | J Mol Cell Cardiol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6579679/ https://ncbi.nlm.nih.gov/pubmed/31085202 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2019.05.006 |
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