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Extracellular matrix components modulate different stages in β(2)-microglobulin amyloid formation
Amyloid deposition of WT human β(2)-microglobulin (WT-hβ(2)m) in the joints of long-term hemodialysis patients is the hallmark of dialysis-related amyloidosis. In vitro, WT-hβ(2)m does not form amyloid fibrils at physiological pH and temperature unless co-solvents or other reagents are added. Theref...
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| Veröffentlicht in: | J Biol Chem |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6579475/ https://ncbi.nlm.nih.gov/pubmed/30996004 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.008300 |
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