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Polygenic Disease and Retinitis Pigmentosa: Albinism Exacerbates Photoreceptor Degeneration Induced by the Expression of a Mutant Opsin in Transgenic Mice

Expression of a mouse opsin transgene containing three point mutations (V20G, P23H, and P27L; termed VPP) causes a progressive photoreceptor degeneration that resembles in many important respects that seen in patients with autosomal dominant retinitis pigmentosa caused by a P23H point mutation. We h...

詳細記述

保存先:
書誌詳細
出版年:J Neurosci
主要な著者: Naash, Muna I., Ripps, Harris, Li, Shihong, Goto, Yoshinobu, Peachey, Neal S.
フォーマット: Artigo
言語:Inglês
出版事項: Society for Neuroscience 1996
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6579236/
https://ncbi.nlm.nih.gov/pubmed/8987813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.16-24-07853.1996
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