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Mitochondrial Dysfunction Is a Primary Event in Glutamate Neurotoxicity

Excitotoxic neuronal death, associated with neurodegenerative disorders and hypoxic insults, results from excessive exposure to excitatory neurotransmitters. Glutamate neurotoxicity is triggered primarily by massive Ca(2+) influx arising from overstimulation of the NMDA subtype of glutamate receptor...

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Pubblicato in:J Neurosci
Autori principali: Schinder, Alejandro F., Olson, Eric C., Spitzer, Nicholas C., Montal, Mauricio
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 1996
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6579180/
https://ncbi.nlm.nih.gov/pubmed/8815895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.16-19-06125.1996
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