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Scavenging 4-Oxo-2-nonenal

4-Oxo-2-nonenal (ONE), a product of cellular lipid oxidation, reacts nonspecifically with the lysine residues of proteins and is generated in increased amounts during degenerative diseases and cancer. We show that pyridoxamine, salicylamine, and related 2-aminomethylphenols react with ONE, to form p...

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Detalles Bibliográficos
Publicado en:Chem Res Toxicol
Main Authors: Amarnath, Venkataraman, Amarnath, Kalyani
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6579115/
https://ncbi.nlm.nih.gov/pubmed/26355561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrestox.5b00301
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