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Systemic Administration of a Nerve Growth Factor Conjugate Reverses Age-Related Cognitive Dysfunction and Prevents Cholinergic Neuron Atrophy
Intraventricular administration of nerve growth factor (NGF) in rats has been shown to reduce age-related atrophy of central cholinergic neurons and the accompanying memory impairment. Intraventricular administration of NGF is necessary because NGF will not cross the blood–brain barrier (BBB). Here...
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| Publié dans: | J Neurosci |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Society for Neuroscience
1996
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6578877/ https://ncbi.nlm.nih.gov/pubmed/8757256 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.16-17-05437.1996 |
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