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Multiple Structural Elements Determine Subunit Specificity of Mg(2+) Block in NMDA Receptor Channels

In NMDA receptor channels, subtype-specific differences of Mg(2+) block are determined by the NR2 subunits. Channels assembled from the NR1-NR2A or NR1-NR2B subunits are blocked more strongly than channels formed by the NR1-NR2C or NR1-NR2D subunits, predominantly reflecting a difference in voltage...

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Detalles Bibliográficos
Publicado en:J Neurosci
Autores principales: Kuner, Thomas, Schoepfer, Ralf
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 1996
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6578835/
https://ncbi.nlm.nih.gov/pubmed/8642401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.16-11-03549.1996
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