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Cell cycle blockers mimosine, ciclopirox, and deferoxamine prevent the death of PC12 cells and postmitotic sympathetic neurons after removal of trophic support

In the present study, we tested whether apoptotic neuronal death caused by withdrawal of trophic support might be prevented by agents that block cell cycle progression. We used three complementary model systems that exhibit apoptotic death: dividing PC12 cells deprived of nerve growth factor (NGF);...

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Foilsithe in:J Neurosci
Main Authors: Farinelli, SE, Greene, LA
Formáid: Artigo
Teanga:Inglês
Foilsithe: Society for Neuroscience 1996
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6578784/
https://ncbi.nlm.nih.gov/pubmed/8558244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.16-03-01150.1996
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