Retinal degeneration in transgenic mice with photoreceptor-specific expression of a dominant-negative fibroblast growth factor receptor

Mutant cDNAs coding for dominant-negative forms of the fibroblast growth factor receptors 1 (FGFR-1) and 2 (FGFR-2) that lack tyrosine kinase activity were ligated to a 2.2 kb DNA fragment containing the bovine rhodopsin promoter and used to generate transgenic mice. Six independent lines were gener...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Campochiaro, PA, Chang, M, Ohsato, M, Vinores, SA, Nie, Z, Hjelmeland, L, Mansukhani, A, Basilico, C, Zack, DJ
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1996
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6578679/
https://ncbi.nlm.nih.gov/pubmed/8774436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.16-05-01679.1996
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