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Bcl-2 overexpression prevents motoneuron cell body loss but not axonal degeneration in a mouse model of a neurodegenerative disease

Bcl-2 and its analogs protect different classes of neurons from apoptosis in several experimental situations. These proteins may therefore provide a means for treatment of neurodegenerative diseases. We examined the effects of Bcl-2 overexpression in a genetic mouse model with motor neuron disease (...

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Bibliografski detalji
Izdano u:J Neurosci
Glavni autori: Sagot, Y, Dubois-Dauphin, M, Tan, SA, de Bilbao, F, Aebischer, P, Martinou, JC, Kato, AC
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 1995
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6578059/
https://ncbi.nlm.nih.gov/pubmed/7472523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.15-11-07727.1995
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