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Bcl-2 overexpression prevents motoneuron cell body loss but not axonal degeneration in a mouse model of a neurodegenerative disease

Bcl-2 and its analogs protect different classes of neurons from apoptosis in several experimental situations. These proteins may therefore provide a means for treatment of neurodegenerative diseases. We examined the effects of Bcl-2 overexpression in a genetic mouse model with motor neuron disease (...

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Podrobná bibliografie
Vydáno v:J Neurosci
Hlavní autoři: Sagot, Y, Dubois-Dauphin, M, Tan, SA, de Bilbao, F, Aebischer, P, Martinou, JC, Kato, AC
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 1995
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6578059/
https://ncbi.nlm.nih.gov/pubmed/7472523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.15-11-07727.1995
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