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Opioid and adenosine peripheral antinociception are subject to tolerance and withdrawal

The selective mu-opioid agonist, D-Ala2,N-Me-Phe4,Gly5-ol-enkephalin (DAMGO), or the selective A1-adenosine agonist N6-cyclopentyladenosine (CPA), when coinjected intradermally with prostaglandin E2 (PGE2), dose- dependently inhibited PGE2-induced mechanical hyperalgesia in the rat hindpaw, as deter...

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Publicat a:J Neurosci
Autors principals: Aley, KO, Green, PG, Levine, JD
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 1995
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6577919/
https://ncbi.nlm.nih.gov/pubmed/8613740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.15-12-08031.1995
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