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AMPA receptor desensitization predicts the selective vulnerability of cerebellar Purkinje cells to excitotoxicity

Cerebellar Purkinje cells are selectively vulnerable to ischemia, although the reasons for this are unknown. In cultured embryonic rat cerebellar neurons, the steady state responses to the desensitizing agonist AMPA relative to responses to the nondesensitizing agonist kainate were greater in Purkin...

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Detalles Bibliográficos
Publicado en:J Neurosci
Main Authors: Brorson, JR, Manzolillo, PA, Gibbons, SJ, Miller, RJ
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 1995
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6577739/
https://ncbi.nlm.nih.gov/pubmed/7540678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.15-06-04515.1995
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