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The mechanism of action for the block of NMDA receptor channels by the opioid peptide dynorphin

Dynorphin is one of the endogenous opioids that modulates the excitability of nociceptive (pain-sensing) neurons. We have shown recently that dynorphin blocks NMDA-activated currents directly without the participation of kappa-opioid receptors. In order to understand the mechanism underlying this no...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Chen, L, Gu, Y, Huang, LY
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6577699/
https://ncbi.nlm.nih.gov/pubmed/7540680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.15-06-04602.1995
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