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NGF regulates the PC12 cell cycle machinery through specific inhibition of the Cdk kinases and induction of cyclin D1
We have examined the effects of NGF on components of the PC12 cell cycle machinery. We show that NGF represses over 6–8 d the levels of specific cdk kinase proteins and the G2-M phase specific cyclin B1 and the S phase marker PCNA as well as the level of phosphorylation of the retinoblastoma (Rb) pr...
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| Yayımlandı: | J Neurosci |
|---|---|
| Asıl Yazarlar: | , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Society for Neuroscience
1995
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6577654/ https://ncbi.nlm.nih.gov/pubmed/7666202 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.15-09-06200.1995 |
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