Peptides containing the RERMS sequence of amyloid beta/A4 protein precursor bind cell surface and promote neurite extension

Amyloid beta/A4 protein precursor (APP) is secreted into medium by most cultured cells and can function as an autocrine factor. To study the biological function of secreted forms of APP (sAPP) on neurons, we used a clonal CNS neuronal line, B103, which does not synthesize detectable levels of APP. B...

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Détails bibliographiques
Publié dans:J Neurosci
Auteurs principaux: Jin, LW, Ninomiya, H, Roch, JM, Schubert, D, Masliah, E, Otero, DA, Saitoh, T
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 1994
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6577069/
https://ncbi.nlm.nih.gov/pubmed/8083748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.14-09-05461.1994
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