Peptides containing the RERMS sequence of amyloid beta/A4 protein precursor bind cell surface and promote neurite extension

Amyloid beta/A4 protein precursor (APP) is secreted into medium by most cultured cells and can function as an autocrine factor. To study the biological function of secreted forms of APP (sAPP) on neurons, we used a clonal CNS neuronal line, B103, which does not synthesize detectable levels of APP. B...

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Publicado en:J Neurosci
Main Authors: Jin, LW, Ninomiya, H, Roch, JM, Schubert, D, Masliah, E, Otero, DA, Saitoh, T
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 1994
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6577069/
https://ncbi.nlm.nih.gov/pubmed/8083748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.14-09-05461.1994
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