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Inactivation of Gi and G(o) proteins in nucleus accumbens reduces both cocaine and heroin reinforcement

The pertussis toxin (PTX)-sensitive G proteins Gi and G(o) may be implicated in drug reinforcement and addiction, since certain reward- related dopamine and opiate receptor subtypes are coupled to these G proteins, and since chronic exposure to cocaine or morphine alters levels of these G proteins i...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Self, DW, Terwilliger, RZ, Nestler, EJ, Stein, L
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6576995/
https://ncbi.nlm.nih.gov/pubmed/7931576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.14-10-06239.1994
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