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Propofol modulates activation and desensitization of GABAA receptors in cultured murine hippocampal neurons

Propofol (2,6 di-isopropylphenol) is an alkyphenol recently introduced for use as a general anesthetic. The modulation of GABAA receptor activation and desensitization by propofol was studied using a rapid perfusion system and whole-cell voltage-clamp recordings from mouse hippocampal neurons. The e...

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Détails bibliographiques
Publié dans:J Neurosci
Auteurs principaux: Orser, BA, Wang, LY, Pennefather, PS, MacDonald, JF
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 1994
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6576906/
https://ncbi.nlm.nih.gov/pubmed/7996209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.14-12-07747.1994
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