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RNA structural analysis of the MYC mRNA reveals conserved motifs that affect gene expression

The MYC gene encodes a human transcription factor and proto-oncogene that is dysregulated in over half of all known cancers. To better understand potential post-transcriptional regulatory features affecting MYC expression, we analyzed secondary structures in the MYC mRNA using a program that is opti...

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Vydáno v:PLoS One
Hlavní autoři: O’Leary, Collin A., Andrews, Ryan J., Tompkins, Van S., Chen, Jonathan L., Childs-Disney, Jessica L., Disney, Matthew D., Moss, Walter N.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6576772/
https://ncbi.nlm.nih.gov/pubmed/31206539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0213758
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