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Transfection with trk restores "slow" NGF binding, efficient NGF uptake, and multiple NGF responses to NGF-nonresponsive PC12 cell mutants

NGF binds to and activates the protein tyrosine kinase gp 140prototrk. Expression of this receptor is required for at least some responses to NGF. Three outstanding issues are addressed in the present work. First, we determined whether expression of gp 140prototrk is required for all neuronal NGF re...

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Vydáno v:J Neurosci
Hlavní autoři: Loeb, DM, Greene, LA
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 1993
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6576685/
https://ncbi.nlm.nih.gov/pubmed/8331380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.13-07-02919.1993
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