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Increased plasma ACTH responses to stress in nonhandled compared with handled rats require basal levels of corticosterone and are associated with increased levels of ACTH secretagogues in the median eminence

Postnatal handling of rat pups is known to alter permanently hypothalamic-pituitary-adrenal (HPA) responses to a wide variety of stressors. As adults, handled (H) and nonhandled (NH) animals also differ in sensitivity to the delayed negative-feedback effects of glucocorticoids on stress-induced HPA...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Viau, V, Sharma, S, Plotsky, PM, Meaney, MJ
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 1993
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6576607/
https://ncbi.nlm.nih.gov/pubmed/8382733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.13-03-01097.1993
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