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Increased plasma ACTH responses to stress in nonhandled compared with handled rats require basal levels of corticosterone and are associated with increased levels of ACTH secretagogues in the median eminence

Postnatal handling of rat pups is known to alter permanently hypothalamic-pituitary-adrenal (HPA) responses to a wide variety of stressors. As adults, handled (H) and nonhandled (NH) animals also differ in sensitivity to the delayed negative-feedback effects of glucocorticoids on stress-induced HPA...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Viau, V, Sharma, S, Plotsky, PM, Meaney, MJ
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6576607/
https://ncbi.nlm.nih.gov/pubmed/8382733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.13-03-01097.1993
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