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Opiates suppress a resting sodium-dependent inward current and activate an outward potassium current in locus coeruleus neurons

The opioid peptide met-enkephalin (met-ENK) produces an outward current with an increase in input conductance in locus coeruleus (LC) neurons. This current has been attributed to an opening of potassium channels. However, the opioid-induced current tends to reverse at potentials more negative than t...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Alreja, M, Aghajanian, GK
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 1993
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6576543/
https://ncbi.nlm.nih.gov/pubmed/8393484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.13-08-03525.1993
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