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Association and release of the amyloid protein precursor of Alzheimer's disease from chick brain extracellular matrix
The amyloid protein precursor (APP) of Alzheimer's disease was found to bind saturably (Kd = 60 nM) to embryonic chick brain extracellular matrix (ECM). The binding of APP to ECM was not inhibited by 10 micrograms/ml heparin or heparan sulfate. However, pretreatment of cells with 1 mM 4-methylu...
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| Publicado no: | J Neurosci |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
1992
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6576018/ https://ncbi.nlm.nih.gov/pubmed/1279136 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.12-11-04143.1992 |
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