Open-channel block of N-methyl-D-aspartate (NMDA) responses by memantine: therapeutic advantage against NMDA receptor-mediated neurotoxicity

Excessive activation of NMDA receptors is thought to mediate the calcium-dependent neurotoxicity associated with hypoxic-ischemic brain injury, trauma, epilepsy, and several neurodegenerative diseases. For this reason, various NMDA antagonists have been investigated for their therapeutic potential i...

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Bibliografiska uppgifter
I publikationen:J Neurosci
Huvudupphovsmän: Chen, HS, Pellegrini, JW, Aggarwal, SK, Lei, SZ, Warach, S, Jensen, FE, Lipton, SA
Materialtyp: Artigo
Språk:Inglês
Publicerad: Society for Neuroscience 1992
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6576016/
https://ncbi.nlm.nih.gov/pubmed/1432103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.12-11-04427.1992
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