Activation and desensitization of AMPA/kainate receptors by novel derivatives of willardiine

Willardiine [(S)-1-(2-amino-2-carboxyethyl)pyrimidine-2,4-dione] is a naturally occurring heterocyclic excitatory amino acid present in the seeds of Acacia and Mimosa. A series of 5-substituted willardiines were synthesized in single enantiomeric forms and tested for activity at AMPA/kainate recepto...

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Veröffentlicht in:J Neurosci
Hauptverfasser: Patneau, DK, Mayer, ML, Jane, DE, Watkins, JC
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 1992
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6575614/
https://ncbi.nlm.nih.gov/pubmed/1371315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.12-02-00595.1992
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