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Structural requirements for novel willardiine derivatives acting as AMPA and kainate receptor antagonists
1. The natural product willardiine is an AMPA receptor agonist. We have examined the structural changes required to convert willardiine into an antagonist at AMPA and kainate receptors. Structure–activity analysis has been carried out to discover the structural features required to increase the pote...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1573755/ https://ncbi.nlm.nih.gov/pubmed/12684265 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705148 |
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