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The novel antagonist 3-CBW discriminates between kainate receptors expressed on neonatal rat motoneurones and those on dorsal root C-fibres

1. The natural product willardiine is a selective AMPA receptor agonist. We report that an N(3)-substituted analogue of willardiine, (S)-3-(4-carboxybenzyl)willardiine (3-CBW), antagonizes AMPA and kainate receptors expressed on motoneurones and dorsal root C-fibres, respectively. 2. Reduction of th...

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Detalhes bibliográficos
Main Authors: More, Julia C A, Troop, Helen M, Jane, David E
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573580/
https://ncbi.nlm.nih.gov/pubmed/12429586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704957
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