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Opioids excite dopamine neurons by hyperpolarization of local interneurons

Increased activity of dopamine-containing neurons in the ventral tegmental area is necessary for the reinforcing effects of opioids and other abused drugs. Intracellular recordings from these cells in slices of rat brain in vitro showed that opioids do not affect the principal (dopamine-containing)...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Johnson, SW, North, RA
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6575608/
https://ncbi.nlm.nih.gov/pubmed/1346804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.12-02-00483.1992
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