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Dopamine and baclofen inhibit the hyperpolarization-activated cation current in rat ventral tegmental neurones.

1. Whole-cell patch-clamp recordings were made from dopamine-containing ventral tegmental area neurones in slices of rat midbrain. An inward current (Ih) was activated by hyperpolarization from -60 mV. 2. Dopamine (30 microM) reduced the amplitude of Ih by 10-30% at potentials from -70 to -120 mV. T...

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Bibliografiska uppgifter
Huvudupphovsmän: Jiang, Z G, Pessia, M, North, R A
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1993
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1175326/
https://ncbi.nlm.nih.gov/pubmed/8392580
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