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Prolonged day length exposure improves circadian deficits and survival in a transgenic mouse model of Huntington's disease
The circadian disruption seen in patients of Huntington's disease (HD) is recapitulated in the R6/2 mouse model. As the disease progresses, the activity of R6/2 mice increases dramatically during the rest (light) period and decreases during the active (dark) period, eventually leading to a comp...
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| Publicado no: | Neurobiol Sleep Circadian Rhythms |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6575567/ https://ncbi.nlm.nih.gov/pubmed/31236493 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbscr.2016.11.004 |
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