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Prolonged day length exposure improves circadian deficits and survival in a transgenic mouse model of Huntington's disease

The circadian disruption seen in patients of Huntington's disease (HD) is recapitulated in the R6/2 mouse model. As the disease progresses, the activity of R6/2 mice increases dramatically during the rest (light) period and decreases during the active (dark) period, eventually leading to a comp...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Neurobiol Sleep Circadian Rhythms
मुख्य लेखकों: Ouk, Koliane, Aungier, Juliet, Morton, A. Jennifer
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Elsevier 2016
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6575567/
https://ncbi.nlm.nih.gov/pubmed/31236493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbscr.2016.11.004
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