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Association of heparan sulfate proteoglycan with the neurofibrillary tangles of Alzheimer's disease

The major intracytoplasmic lesion of Alzheimer's disease is the neurofibrillary tangle (NFT), which is primarily composed of paired helical filaments (PHFs). The mechanism responsible for the formation of PHFs, as well as their insolubility and apparent heterogeneity, is unknown. We found that...

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Publicat a:J Neurosci
Autors principals: Perry, G, Siedlak, SL, Richey, P, Kawai, M, Cras, P, Kalaria, RN, Galloway, PG, Scardina, JM, Cordell, B, Greenberg, BD
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 1991
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6575552/
https://ncbi.nlm.nih.gov/pubmed/1941102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.11-11-03679.1991
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