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Association of heparan sulfate proteoglycan with the neurofibrillary tangles of Alzheimer's disease

The major intracytoplasmic lesion of Alzheimer's disease is the neurofibrillary tangle (NFT), which is primarily composed of paired helical filaments (PHFs). The mechanism responsible for the formation of PHFs, as well as their insolubility and apparent heterogeneity, is unknown. We found that...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Perry, G, Siedlak, SL, Richey, P, Kawai, M, Cras, P, Kalaria, RN, Galloway, PG, Scardina, JM, Cordell, B, Greenberg, BD
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6575552/
https://ncbi.nlm.nih.gov/pubmed/1941102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.11-11-03679.1991
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