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The N-methyl-D-aspartate antagonist, MK-801, fails to protect against neuronal damage caused by transient, severe forebrain ischemia in adult rats

The neuroprotective effects of dizocilipine maleate (MK-801), a noncompetitive antagonist of the N-methyl-D-aspartate (NMDA) receptor/channel, were tested in the 4-vessel occlusion rat model of forebrain ischemia. Adult Wistar rats, treated intraperitoneally with MK-801 or saline using several diffe...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Buchan, A, Li, H, Pulsinelli, WA
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 1991
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6575368/
https://ncbi.nlm.nih.gov/pubmed/2010804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.11-04-01049.1991
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