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The Alzheimer amyloid precursor is associated with the detergent- insoluble cytoskeleton

The amyloid beta-protein (A beta P), the main component of neuritic plaques in Alzheimer's disease (AD), is derived by unknown mechanisms from a family of amyloid precursor proteins (APPs). Using a detergent extraction procedure, we have found that in brain and in neural cell lines, 50-90% of A...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Refolo, LM, Wittenberg, IS, Friedrich, VL, Robakis, NK
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6575273/
https://ncbi.nlm.nih.gov/pubmed/1683901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.11-12-03888.1991
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