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Replisome activity slowdown after exposure to ultraviolet light in Escherichia coli

The replisome is a multiprotein machine that is responsible for replicating DNA. During active DNA synthesis, the replisome tightly associates with DNA. In contrast, after DNA damage, the replisome may disassemble, exposing DNA to breaks and threatening cell survival. Using live cell imaging, we stu...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Soubry, Nicolas, Wang, Andrea, Reyes-Lamothe, Rodrigo
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6575178/
https://ncbi.nlm.nih.gov/pubmed/31127046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1819297116
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