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Replisome activity slowdown after exposure to ultraviolet light in Escherichia coli
The replisome is a multiprotein machine that is responsible for replicating DNA. During active DNA synthesis, the replisome tightly associates with DNA. In contrast, after DNA damage, the replisome may disassemble, exposing DNA to breaks and threatening cell survival. Using live cell imaging, we stu...
Enregistré dans:
| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6575178/ https://ncbi.nlm.nih.gov/pubmed/31127046 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1819297116 |
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