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High Folic Acid Supplementation Reprograms Glycolytic and Lactate-generating Metabolism to Promote Anchorage-independent Tumor Spheroid Formation in NSCLC Cells (P05-001-19)

OBJECTIVES: Aims of this study were to investigate the effect of HF on anchorage-independent tumor spheroid formation and its’ working mechanisms of lung malignant tumor cells. METHODS: Human NSCLC cells A549 were cultured in control (C) medium (2.2 μM folic acid) or HF medium (10, 30, 50 μM folic a...

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Bibliographische Detailangaben
Veröffentlicht in:Curr Dev Nutr
Hauptverfasser: Chen, Yi-Wen, Huang, Rwei-Fen S
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6574006/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cdn/nzz030.P05-001-19
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