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Dissociation of Tolerance and Dependence for Opioid Peripheral Antinociception in Rats
Repeated peripheral administration of the μ-opioid agonist [d-Ala(2),N-Me-Phe(4),gly(5)-ol] enkephalin (DAMGO) produces acute tolerance and dependence on its peripheral antinociceptive effect against prostaglandin E(2)(PGE(2))-induced mechanical hyperalgesia. In this study we evaluated the roles of...
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| Publicado no: | J Neurosci |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
1997
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6573706/ https://ncbi.nlm.nih.gov/pubmed/9133408 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.17-10-03907.1997 |
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